MGIT BRONCHOSCOPIC BRONCHOSCOPIC LAVAGE FOR THE DIAGNOSIS IN SPUTUM-SMEAR NEGATIVE PULMONARY TUBERCULOSIS
Overview
Abstract:
Summary
Objectives: Evaluation and
compare values of MGIT, Xpert MTB/RIF and ZN for bronchoscopy bronchoscopic
lavage for the diagnosis in sputum-smear negative pulmonary tuberculosis. Methods: Descriptive study at Thai
Nguyen Tuberculosis and Lung Disease Hospital, from 1 / 2020-12 / 2020. There
were 90 patients with suspected tuberculosis in sputum-smear negative or less
sputum. MGIT, Xpert MTB/RIF and ZN of bronchoscopy bronchoscopic lavage. Results: MGIT assay against the
standard with combined TB diagnosis had a sensitivity of 72.5%, a specificity
of 71.4%, a positive predictive value of 89.3% and a negative predictive value
44,1%. The MGIT test against the Xpert MTB/RIF standard for TB diagnosis had a
sensitivity of 64.3%, a specificity of 82.4%, a positive predictive value of
85.7% and a negative predictive value of 58.3%. Discussions: Together as were bronchoscopy bronchoscopic lavages,
the TB diagnostic sensitivity of MGIT was always higher than ZN. Conclusions: Bronchoalveolar bronchial
lavage MGIT test were more effective in diagnosing pulmonary tuberculosis than
ZN in patients with suspected TB, in sputum-smear negative and less sputum.
Keyword(s): pulmonary tuberculosis, sputum-smear negative, MGIT, Xpert MTB/RIF, ZN.
Journal | Journal of Practical Medicine |
Volume | 501 |
Issue number | 2 |
Publication status | Published - Apr-2001 |
ISBN | 1859-1663 |