Comparison of characteristics in patients with sepsis caused by gram negative and gram positive bacteria at Thai Nguyen National hospital 2020-2023

The Assessors of the Asian University Network - Quality Assurance (AUN-QA) are warmly welcomed!

Welcome to the Vietnamese Doctors’ Day!

Abstract:

COMPARISON OF CHARACTERISTICS IN PATIENTS WITH SEPSIS 

CAUSED BY GRAM NEGATIVE AND GRAM POSITIVE BACTERIA

AT THAI NGUYEN NATIONAL HOSPITAL (2020 - 2023)

Summary 

Objectives:

 Compare some epidemiology, clinical and subclinical characteristics of patients with sepsis 

caused by gram negative (GN) and gram positive (GP) bacteria.

Subject and methods:

  Retrospective  study  on  156  patients  diagnosed  with  sepsis  according  to  the 

standard of the Ministry of Health in 2015.

Results and conclusions:

 GN bacteria is the cause of sepsis with the highest proportion 121 (77.6%); 

GP bacteria accounts for less than 35 (22.4%). The most common GN bacteria is 

E.coli

63

(40K. pneumonia

 28 (17.9%), the most common GP pathogen is S. aureus 27 (17.3%). Patients with sepsis 

having fever with chill and primary infection in the urinary tract accounted for a higher proportion in the 

GN group than in the GP group, a difference of p = 0.0000, p = 0.006. The proportion of sepsis patients with 

primary infection in the skin and mucous membranes in the GP group 16/35 (45.7%) was higher than the 

GN group 7/121 (5.8%), a difference with p = 0.000. The number of white blood cells and blood platelets 

in patients with sepsis due to GN was lower than that of GP, with a difference of p = 0.029 and p = 0.019. 

There is no statistically significant difference in the mean value of PCT between the two groups of patients 

with respiratory tract infections due to GN and GP. The average CRP value in the VK GP group (164.23 ± 

109.66) was higher than the VK GN group (121.03 ± 76.54), which was statistically significant with p = 

0.011.

Recommendations:

 GN is the most common cause of sepsis. The patient has clinical characteristics of 

fever with chill, primary infection in the urinary tract, low platelet count which help suggest the cause of 

sepsis, often with GN bacteria. The primary source of infection in the skin, mucous membranes, suggests 

that the common cause of sepsis is GP bacteria.

Keywords:

 Sepsis, clinical, subclinical, Thai Nguyen, Gram negative, Gram positive bacteria.

.4%); 

Article number	20
Journal	Vietnam Journal of Infectious Diseases
Volume	Số đặc biệt
Publication status	Published - Sep-2024
ISBN	0866-7829