Background: Obstructive Sleep Apnea (OSA) is a condition characterized by recurrent, intermittent obstruction of the airflow through the nose and mouth, leading to disruption of sleep physiology, impaired daytime function, and an increased risk of cardiovascular and metabolic diseases. Numerous studies in Vietnam indicate that a majority of patients over 65 years old exhibit signs of OSA across various severities. However, most remain undiagnosed and untreated promptly due to limited awareness, difficulty in detection, and lack of access to specialized diagnostic testing.. Objective: Describe the characteristics of risk associated with obstructive sleep apnea in elderly patients presenting at Thai Nguyen University of Medicine and Pharmacy Hospital. Method: A descriptive cross-sectional study design was employed, involving 86 patients presenting with signs of obstructive sleep apnea at Thai Nguyen University of Medicine and Pharmacy in 2025. Result: Among the total of 86 patients studied, 80.2% of patients with hypertension and 84.0% of patients with diabetes exhibited signs of OSA. Patients usually experienced symptoms such as snoring, dry mouth, and mouth breathing during sleep, with respective prevalence rates of 34.9%, 31.4%, and 29.1%. Daytime symptoms included impaired memory (38.4%), reduced concentration (30.2%), and non-restorative sleep upon waking (26.7%). The mean Epworth Sleepiness Scale (ESS) score for the group with OSA was 6.79±3.24, higher than the group without OSA (3.76±2.75). Additionally, 65.2% of the studied patients with signs of OSA were assessed as high risk according to the STOP-BANG screening tool. Conclusions: The prevalence of Obstructive Sleep Apnea is trending upward in elderly patients, particularly those with obesity and a large, short neck. Common nocturnal symptoms include snoring, mouth breathing during sleep, dry mouth, and frequent awakenings. During the day, patients frequently manifest symptoms such as memory impairment, reduced concentration, and morning fatigue. The utilization of the Epworth Sleepiness Scale (ESS), STOP-BANG, and STOP-B28 questionnaires is valuable for assessing OSA risk and daytime sleepiness, facilitating effective screening and treatment monitoring in patients presenting with signs of OSA, demonstrated by high sensitivity.