Objectives: Describe the characteristics and relationship between motor complications and quality of life in patients with parkinsons stage 3 and 4 according to Hoehn and Yahr (H&Y). Methods: Cros-sectional, descriptive study. Results: 99 PD patients (46 male/53 female) in stage 3 and 4 by Hoehn and Yahr (69.3% in stage 3), treated at National Geriatric Hospital from August 2019 to May 2020. The average S&E-ADL and PD-SI scores of the study subjects were 52.63±13.16 and 50.64±14.71, respectively; The mean scores of "motor", "daily activity", "cognition" and "body discomfort" were higher in the group with motor complications compared with the other group of patients (p<0.05). There was a difference in quality of life scores in patients with “Dose failure”, “Unpredictable wearing-off”, “off-phase dyskinesia”, “biphasic dyskinesia” and “morning dystonia” compared with patients without the above complications. Conclusion: Motor complications greatly affect the quality of life of parkinsonian patients, especially the complication of “dose failure” “unpredictble wearing-off”, “off-phase dyskinesia”, “biphasic dyskinesia” and “morning dystonia”.