RELATIONSHIP BETWEEN THE BILIRUBIN TOTAL AND DEGREE OF CORONARY ARTERY DISEASE AT THAINGUYEN NATIONAL HOSPITAL
B K. C., Apr-2021, In: Vietnam Medical Journal
Overview
Abstract:
Bilirubin is believed to have protective effects in
coronary artery disease. The relationship between the
total plasma bilirubin concentration and the degree of coronary artery damage needs to be further
between the concentration of total bilirubin in plasma
with the level of coronary artery injury assessed by
Gensini scale in patients with an indication for coronary
angiography at ThaiNguyen National Hospital.
Methods: Cross-sectional descriptive study on 84
patients had a coronary scan at ThaiNguyen National
Hospital from March 2020 to February 2021. Results:
The mean total plasma bilirubin concentration was
12.57±5.39µmol/L. There was no difference in mean
bilirubin concentration between the sexes and the age
groups (p>0.05). The group with total plasma bilirubin
concentration <17.1µmol/l had a narrow coronary
heart rate ≥ 50%, which was 88.9% higher than the
group with total bilirubin concentration ≥17.1µmol/l,
the rate of narrow ≥ 50% is 57.1%. The difference is
statistically significant (OR = 0.2; 95% CI: 0.05 - 0.54;
p <0.01). The mean total plasma bilirubin
concentration decreased with severity of coronary
artery damage according to the mild Gensini score of
15.93 ± 5.17; the mean Gensini score was 12.72 ±
5.15; Gensini severity score was 9.51 ± 3.87, with p
<0.001. There is a quite strong inverse correlation
between the concentration of total bilirubin in plasma
with Gensini score assessing the level of coronary
damage in patients with coronary artery disease (r = -
0.52, p <0.05). Conclusion: Low plasma bilirubin
concentration is associated with severe coronary artery
damage (≥50% stenosis and Gensini score); There was
a fairly strong inverse relationship with the degree of
coronary injury calculated on the Gensini score (r = -
0.52, p <0.001)
Keyword(s): Total bilirubin, coronary artery damage, Gensini score.
| Journal | Vietnam Medical Journal |
| Publication status | Published - Apr-2021 |
| ISBN | 1859-1868 |