Ngà hoóc is a plant for seeds grown and used popularly by the highland ethnic people in Quang Uyen district, Cao Bang province. According to the local language "Ngà hoóc " which means "hard sesame", the indigenous people always consider this a sesame variety and the use of Ngà hoóc seeds has many similarities with the use of sesame seeds such as: making sesame salt, making sesame seeds, and making sesame seeds, making cake filling... However, when surveyed in the field, Ngà hoóc has many morphological characteristics of the family Lamiaceae. Therefore, this study was conducted to describe morphological characteristics and microscopic analysis of Ngà hoóc. At the same time, conduct qualitative determination of the chemical composition in the seeds of Ngà hoóc. Research results have described in detail the morphological characteristics of the parts: leaves, stems, flowers, fruits, and analyzed microscopically of leaves and stems. Thereby determining the scientific name of the Ngà hoóc is Perilla frutescens var.frutescens, belonging to the genus Perilla, family Lamiaceae, commonly known as white perilla. The results of qualitative chemical composition showed that, in Ngà hoóc seeds contain groups of substances: fats, carotenoids, essential oils, hydrolyzed triterpenoids, alkaloids, flavonoids, organic acids, reducing agents