Survey on some clinical andsubclinical features of eye lesions and TRAb concentration in patients with Graves’ disease
Overview
Abstract:
Objectives: To survey some clinical and subclinical features of eye lesions and TRAb 
concentration in patients with Graves’ disease. Subjects and methods: A descriptive crosssectional study in 82 patients with Graves’ ophthalmopathy. They were treated at the National 
Hospital of Endocrinology. The research method was used a descriptive cross-sectional study. 
Results: Median age was 34.0. The median duration of Graves' disease was 1.53 years. Some 
common clinical symptoms were lacrimation (87.8%), conjunctival congestion (52.4%), and 
eyelid retraction (76.8%). 100% of patients had elevated TRAb levels. The median level of 
TRAb was 8.97 (lU/mL). Through orbital computed tomography, there were 32.9% of patients 
with ocular muscle hypertrophy. Inferior rectus muscle hypertrophy accounted for the most 
common rate. Conclusion: Clinical manifestations of Graves’ ophthalmopathy were abundant. 
TSH-receptor autoantibody (TRAb) levels TRAb autoantibodies increased in patients with 
Graves’ ophthalmopathy. Orbital tomography is valuable in diagnosing exophthalmos and 
extraocular muscle hypertrophy in Graves’ ophthalmopathy. 
Keyword(s): Graves’ ophthalmopathy; Graves’ disease.
| Article number | 156 | 
| Journal | Journal of Military Medicine | 
| Volume | Vol 46 | 
| Issue number | N 6 – 2021 | 
| Publication status | Published - Aug-2021 | 
| ISBN | 1859-0748 | 
