Survey on some clinical andsubclinical features of eye lesions and TRAb concentration in patients with Graves’ disease
Overview
Abstract:
Objectives: To survey some clinical and subclinical features of eye lesions and TRAb
concentration in patients with Graves’ disease. Subjects and methods: A descriptive crosssectional study in 82 patients with Graves’ ophthalmopathy. They were treated at the National
Hospital of Endocrinology. The research method was used a descriptive cross-sectional study.
Results: Median age was 34.0. The median duration of Graves' disease was 1.53 years. Some
common clinical symptoms were lacrimation (87.8%), conjunctival congestion (52.4%), and
eyelid retraction (76.8%). 100% of patients had elevated TRAb levels. The median level of
TRAb was 8.97 (lU/mL). Through orbital computed tomography, there were 32.9% of patients
with ocular muscle hypertrophy. Inferior rectus muscle hypertrophy accounted for the most
common rate. Conclusion: Clinical manifestations of Graves’ ophthalmopathy were abundant.
TSH-receptor autoantibody (TRAb) levels TRAb autoantibodies increased in patients with
Graves’ ophthalmopathy. Orbital tomography is valuable in diagnosing exophthalmos and
extraocular muscle hypertrophy in Graves’ ophthalmopathy.
Keyword(s): Graves’ ophthalmopathy; Graves’ disease.
Article number | 156 |
Journal | Journal of Military Medicine |
Volume | Vol 46 |
Issue number | N 6 – 2021 |
Publication status | Published - Aug-2021 |
ISBN | 1859-0748 |